Project information
Phenotype dynamics in patient treated by paroxetine regarding the clinical correlates
- Project Identification
- NF6159
- Project Period
- 1/2000 - 1/2002
- Investor / Pogramme / Project type
-
Ministry of Health of the CR
- R&D of Neurology and Psychiatry
- MU Faculty or unit
- Faculty of Medicine
The aim of the project is to establish the role of CYP 2D6 genetic polymorphism with to the efficacy and drug safety of treatment of anxiety disorders with paroxetine and duration of metabolic phenotype conversion within treatment discontinuation.
Publications
Total number of publications: 14
2001
-
Dynamics of clinical response to paroxetine in coherence with CYP 2D6 metabolic status during long-term therapy of depressive disorder.
South African Journal of Science, year: 2001, volume: 55, edition: 6
-
Effect of mirtazapine and paroxetine on residual symptoms of depressive disorders and their effect on P450 CYP 2D6 activity
Homeostasis, year: 2001, volume: 41, edition: 6
-
Sexuální funkce při léčbě paroxetinem
Psychiatrie, year: 2001, volume: 5, edition: suppl.1
1997
-
Influence of LPS and its combination with aminoguanidine on the pharmacokinetics of procainamide in rats
Naunyn-Schmiedebergs Arch. Pharmacol, year: 1997, volume: 355, edition: suppl.