Project information
The yeast cell wall as an extracellular matrix: cytoskeleton and cell wall functions
- Project Identification
- GA204/00/0394
- Project Period
- 1/2000 - 1/2002
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Medicine
In terms of origin, chemical composition and structure, the cell wall can be regarded as an extracellular matrix, but evidence of its structural and functional relation to the cytoplasm is still missing. The objective of the project is to elucidate relat ionships between cytoskeletal components (actin and tubulin) and the cell wall during its growth, de novo formation, in the period of increased turnover, i.e., during cell vegetative growth, at mating, at sporulation and during protoplast regeneration. T he project will also include investigations into links between the cytoplasm and cell wall by means of transmembrane proteins of integrin type, into molecular linkers between the cytoskeleton and transmembrane proteins and into interactions between these proteins and cell wall polymers. The microorganisms used as models will be the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe in various phases of the cell cycle, the protoplasts of these species during regenerati
Publications
Total number of publications: 17
2003
-
Immunodetection of Spectrin-like Proteins in Yeasts
Canadian Journal of Microbiology, year: 2003, volume: 49, edition: 3
2002
-
Detection of spectrin-like protein in yeasts: spectrin-actin relations
Sborník X. Cytoskeletálního klubu, year: 2002
-
Spectrin-like protein in yeasts
Sborník XXX th Annual Conference on yeasts, year: 2002
2001
-
Cytoskeleton in regenerating protoplasts and restoration of cell polarity in the yeast Saccharomyces cerevisiae
Acta Biologica Hungarica, year: 2001, volume: 52, edition: 2
-
Lokalizace spektrinu (spektrinu podobného) proteinu u kvasinek
In IX. Cytoskeletální klub, year: 2001
2000
-
A response of yeast cells to heat stress: cell viability and the stabilitz of cytoskeletal structures
Scripta medica, year: 2000, volume: 73, edition: 6
-
Buněčný stres a stabilita cytoskeletu
VIII. Cytoskeletání klub, year: 2000
-
Buněčný stres a stabilita kvasinkového cytoskeletu
In sborník XXVIII. Výroční konference o kvasinkách, year: 2000
-
Cytoskeleton and mitochondrial topology in Xantophyllomyces dendrorhous (Phaffia rhodozyma)
Folia Microbiologica, year: 2000, volume: 45, edition: 1
-
Cytoskeleton and morphological aberrations of septum formation and cytokinesis in cps6 mutant of Schizosaccharomyces pombe
VII. Cytoskeletální klub, year: 2000