Project information
Electro-Conductive Biomaterials (Elektricky vodivé biomateriály)

Information

This project doesn't include Faculty of Medicine. It includes Faculty of Science. Official project website can be found on muni.cz.
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Project Identification
GA23-07425S
Project Period
1/2023 - 12/2025
Investor / Pogramme / Project type
Czech Science Foundation
MU Faculty or unit
Faculty of Science
Cooperating Organization
Tomas Bata University in Zlín

Material properties such as topography, surface chemistry, architecture, and electrical conductivity influence cell fate. Present knowledge on the interaction between materials and cells is, however, predominantly based on cultivation conditions that bias cells away from a physiological state. The proposed project is therefore directed towards research into the preparation of 1) planar materials with defined surface properties, and 2) scaffolds with a defined architecture and composition, and the testing of their interactions with pluripotent stem cells (including induced human pluripotent stem cells) under in vivo simulated conditions. For the preparation of biomaterials, advanced techniques, e.g. the 3D printing of plastics and metals, phase separation, plasma etching, laser patterning, and 3D laser sintering, will be employed. In vivo conditions will be simulated by specially designed and fabricated cultivation chambers and commercial bioreactors. The results should fill a gap in knowledge crucial for successful tissue engineering.

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