Project information
Novel pathway of FGFR3 signaling in achondroplasia
- Project Identification
- GA301/09/0587
- Project Period
- 3/2009 - 12/2011
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Science
- Keywords
- FGFR3, inhibitor, molecular library, cartilage, chondrocyte, kinase, achondroplasia
Publications
Total number of publications: 8
2012
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Apoptosis inhibitor 5 (API-5; AAC-11; FIF) is upregulated in human carcinomas in vivo
Oncology Letters, year: 2012, volume: 3, edition: 4, DOI
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p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice.
The journal of clinical investigation, year: 2012, volume: 122, edition: 6, DOI
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Sixteen years and counting: the current understanding of fibroblast growth factorreceptor 3 (FGFR3) signaling in skeletal dysplasias.
Human Mutation, year: 2012, volume: 33, edition: 1, DOI
2011
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Mitogen-Activated Protein Kinases Promote WNT/beta-Catenin Signaling via Phosphorylation of LRP6
Molecular and cellular biology, year: 2011, volume: 31, edition: 1, DOI
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Post-translational modifications regulate signalling by Ror1
Acta Physiologica, year: 2011, volume: 203, edition: 3, DOI
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The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting insuppression of human myeloma cell growth and survival.
Leukemia, year: 2011, volume: 25, edition: 3, DOI
2010
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FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence
Bone, year: 2010, volume: neuveden, edition: 47
2009
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Molecular pathology of the fibroblast growth factor family.
Human Mutation, year: 2009, volume: 30, edition: 9, DOI