Project information
The expression of basic fibroblast growth factor (FGF-2) and FGF-receptors in human leukemic cells. Potential use for the monitoring of cancer therapy

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Project Identification
GA312/97/0393
Project Period
1/1997 - 1/1999
Investor / Pogramme / Project type
Czech Science Foundation
MU Faculty or unit
Faculty of Medicine
Cooperating Organization
Institute of Animal Physiology and Genetics of thr ASCR, v. v. i.
University Hospital Brno-Bohunice

The main objective of this project is to investigate the expression of FGF-2 and FGFR in peripheral blood and the level of secreted FGF-2 in blood and urine of patients with selected with selected lymphoid and myeloid leukemias as a potential monitor of cancer therapy. The results will be correlated with the stage of disease and the underwent treatment. A complementary scientific objectives are to characterize the carbohydrate composition in leukemic cells and to probe the possibility to regulate in vit

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