Project information
Structural characterisation of the interplay between transcription and DNA repair

Information

This project doesn't include Faculty of Medicine. It includes Central European Institute of Technology. Official project website can be found on muni.cz.

Project Identification

GM21-10464M

Project Period

1/2021 - 12/2025

Investor / Pogramme / Project type

Czech Science Foundation

JUNIOR STAR

MU Faculty or unit

Central European Institute of Technology

Mgr. Marek Šebesta, Ph.D.

In the proposed research project, we will investigate the interaction between transcription and DNA repair at molecular level.

Sustainable Development Goals

Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.

Publications

Total number of publications: 2

2023

Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor

HAŠANOVÁ Zdenka KLÁPŠŤOVÁ Veronika PORRUA Odil ŠTEFL Richard ŠEBESTA Marek

Article in Periodical

Nucleic Acids Research, year: 2023, volume: 51, edition: 6, DOI
The phosphorylated trimeric SOSS1 complex and RNA polymerase II trigger liquid-liquid phase separation at double-strand breaks

LONG Qilin ŠEBESTA Marek ŠEDOVÁ Kateřina HALUZA Vojtěch ALAGIA Adele LIU Zhichao ŠTEFL Richard GULLEROVA Monika

Article in Periodical

Cell Reports, year: 2023, volume: 42, edition: 12, DOI

Project informationStructural characterisation of the interplay between transcription and DNA repair

Information

Sustainable Development Goals

Publications

2023

Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor

The phosphorylated trimeric SOSS1 complex and RNA polymerase II trigger liquid-liquid phase separation at double-strand breaks

Project information
Structural characterisation of the interplay between transcription and DNA repair