Project information
The role of membrane currents in electrical and mechanical restitution of cardiac cells.
- Project Identification
- GA305/97/0043
- Project Period
- 1/1997 - 1/1999
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Medicine
The project is aimed at clarification of some less well understood moieties of the excitation-contraction coupling, namely: (a) to contribute by partial indirect proofs to the clarification of the nature of mechanical restitution ; (b) to define the cont ribution and significance of ionic membrane current components for the variations of the action potential configuration particularly in the course of electrical restitution; (c ) to contribute to the explanation of the species differences in electromech
Publications
Total number of publications: 5
2001
-
Quantitative analysis of cardiac electrical restitution
European Biophysics Journal, year: 2001, volume: 2001, edition: September
1999
-
Propafenone blocks ATP-sensitive K+ channels in rabbit atrial and ventricular cardiomyocytes.
European Journal of Pharmacology, year: 1999, volume: 373, edition: 2-3
-
Quantitative modelling of 4-aminopzridine block of transient outward current
Physiological Research, year: 1999, volume: 1999, edition: Suppl 1
1997
-
Kinetics of propafenone-induced block of sodium current in rat ventricular myocytes
Scripta medica, year: 1997, volume: 70, edition: 6
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Užití matematického modelování při zpracování dat a optimalizaci měření účinků farmak na membránové kanály
Inženýrská mechanika 97., year: 1997