Project information
Molecular basis of cell and tissue regulations
- Project Identification
- MSM0021622415
- Project Period
- 1/2005 - 12/2011
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Central European Institute of Technology
- Other MU Faculty/Unit
- Faculty of Medicine
- Keywords
- Cell; genomics; proteomics; biomedicine; gene expression; regulation mechanisms; chromatin structure; structure and interactions of biomolecules
The cell is a system in which each molecule is a component of interaction network. Due to the highly complex interconnection, function of cells and organisms is relatively resistant to failure of individual components of the network. Convergence of thought and methodical approaches which is characteristic for today’s postgenomic era, is a basis for interconnection of research capacities of molecular-biology oriented workgroups of the Masaryk University in the proposed Research Plan (RP). Solving of the RP will proceed in 4 program areas: 1. Regulation mechanisms in animal cells; 2. Functional domains of eukaryotic chromosomes; 3. Genomics and proteomics of regulation circuits in plants; 4. Functional analysis of the genome of clinically and biotechnologically important bacteria. The RP objective is to use approaches of structural biology, functional genomics, proteomics and bioinformatics to elucidate molecular basis of processes which are important from the viewpoint of perspective biomedical and biotechnology applications.
Publications
Total number of publications: 1210
2005
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PROTEOMIC STRATEGY FOR INVESTIGATIGATION OF CYTOKININ ACTION IN ARABIDOPSIS THALIANA
Molecular and cellular proteomics, year: 2005
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Přírodní zdroje nákazy lymeské borreliózy - hlodavci a jejich paraziti
Year: 2005, type: Conference abstract
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Racemic monoperoxovanadium(V) complexes with achiral OO and ON donor set heteroligands: synthesis, crystal structure and stereochemistry of [NH3(CH2)(2)NH3][VO(O-2)(ox)(pic)].2H(2)O and [NH3(CH2)(2)NH3][VO(O-2)(ox)(pca)]
Dalton transactions : an international journal of organic chemistry, year: 2005, volume: 2005, edition: 13
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Regulace a význam exprese vimentinu při diferenciaci monoblastů tranformovaných onkogenem v-myb
Sborník příspěvků IX. pracovního setkání biochemiků a molekulárních biologů, year: 2005
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Reproducibility of Comparative Genomics Sequencing in Treponema pallidum ssp. pallidum.
Year: 2005, type: Conference abstract
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Reproduction of Plants
Encyclopedia of Molecular Cell Biology and Molecular Medicine, edition: Vyd. 2., year: 2005, number of pages: 47 s.
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Restrikční mapování genomů blízce příbuzných patogenních spirochet rodu Treponema.
Year: 2005, type: Conference abstract
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Restrikční mapování genomů blízce příbuzných spirochet rodu Treponema.
Chemické listy, year: 2005
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Retargetting a maize beta-glucosidase: Evidence from intact plants that zeatin-O-glucoside is stored in the vacuole.
Biologia Plantarum 49 (Suppl.), 2nd International Symposium Auxins and Cytokinins in Plant Development, year: 2005
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Sensitive determination of food colorant erythrosine and other xanthene dyes by CE-LIF
Book of Abstracts - 11th International Symposium on Separation Sciences 2005, year: 2005