MUDr. Roman Hakl, Ph.D.

2022

• OPTIMIZATION OF IN-VITRO DIFFERENTIATION AND ACTIVATION OF MONOCYTES BEFORE THE ANALYSIS OF PLAUR GENE EXPRESSION

  SLANINA Peter ŠTÍCHOVÁ Julie KULÍŠKOVÁ Petra BALLONOVÁ Lucie BAROŠ Jan LITZMAN Jiří VLKOVÁ Marcela SOUČEK Přemysl FREIBERGER Tomáš HAKL Roman

  Conference abstract

  Year: 2022, type: Conference abstract

• Registry-based analysis of Icatibant and C1-inhibitor use in treatment of laryngeal attacks of hereditary angioedema

  HAKL Roman KUKLÍNEK Pavel SOBOTKOVA Marta KRCMOVA Irena KRALICKOVA Pavlina VACHOVA Martina HANZLIKOVA Jana NOVACKOVA Martina SVOBODA Michal KOVÁČOVÁ Ingrid LITZMAN Jiří

  Article in Periodical

  CLINICAL AND EXPERIMENTAL ALLERGY, year: 2022, volume: 52, edition: 8, DOI

• Risk Factors for Severe COVID-19 and Hospital Admission in Patients With Inborn Errors of Immunity-Results From a Multicenter Nationwide Study

  MILOTA Tomas SOBOTKOVA Marta SMETANOVA Jitka BLOOMFIELD Marketa VYDLAKOVA Jana CHOVANCOVÁ Zita LITZMAN Jiří HAKL Roman NOVAK Jiri MALKUSOVA Ivana HANZLIKOVA Jana JILEK Dalibor HUTYROVA Beata NOVAK Vitezslav KRCMOVA Irena SEDIVA Anna KRALICKOVA Pavlina

  Article in Periodical

  Frontiers in Immunology, year: 2022, volume: 13, edition: February 2022, DOI

2021

• A spectrum of SERPING1 mutations and clinical characterisation of Czech Hereditary Angioedema patients.

  GROMBIŘÍKOVÁ Hana RAVČUKOVÁ Barbora GRODECKÁ Lucie HUJOVÁ Pavla HAKL Roman KUKLÍNEK Pavel ZACHOVÁ Radana SOBOTKOVÁ M. KRÁLÍČKOVÁ Pavlína KRYŠTŮVKOVÁ Olga ŠEDIVÁ Anna LITZMAN Jiří FREIBERGER Tomáš

  Conference abstract

  Year: 2021, type: Conference abstract

• Acquired Angioedema with C1 Inhibitor Deficiency: Occurrence, Clinical Features, and Management: A Nationwide Retrospective Study in the Czech Republic Patients

  SOBOTKOVA Marta ZACHOVA Radana HAKL Roman KUKLÍNEK Pavel KRALICKOVA Pavlina KRCMOVA Irena HANZLIKOVA Jana VACHOVA Martina BARTUNKOVA Jirina

  Article in Periodical

  International archives of allergy and immunology, year: 2021, volume: 182, edition: 7, DOI

• Alternative splicing of PLAUR gene in macrophage differentiation stages of hereditary angioedema patients

  BALLONOVÁ Lucie SOUČEK Přemysl SLANINA Peter HAKL Roman VLKOVÁ Marcela FREIBERGER Tomáš

  Conference abstract

  Year: 2021, type: Conference abstract

• Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial

  ZURAW B. LUMRY W. R. JOHNSTON D. T. AYGOREN-PURSUN E. BANERJI A. BERNSTEIN J. A. CHRISTIANSEN S. C. JACOBS J. S. SITZ K. V. GOWER R. G. GAGNON R. WEDNER H. J. KINACIYAN T. HAKL Roman HANZLIKOVA Jana ANDERSON J. T. MCNEIL D. L. FRITZ S. B. YANG W. H. TACHDJIAN R. BUSSE P. J. CRAIG T. J. LI H. H. FARKAS H. BEST J. M. CLEMONS D. CORNPROPST M. DOBO S. M. IOCCA H. A. KARGL D. NAGY E. MURRAY S. C. COLLIS P. SHERIDAN W. P. MAURER M. RIEDL M. A.

  Article in Periodical

  Journal of allergy and clinical immunology, year: 2021, volume: 148, edition: 1, DOI

• Recombinant human C1 esterase inhibitor for hereditary angioedema attacks: A European registry

  VALERIEVA A. STAEVSKA M. T. GRIVCHEVA-PANOVSKA V. JESENAK M. KOHALMI K. V. HRUBISKOVA K. ZANICHELLI A. BELLIZZI L. RELAN A. HAKL Roman FARKAS H.

  Article in Periodical

  WORLD ALLERGY ORGANIZATION JOURNAL, year: 2021, volume: 14, edition: 4, DOI

2020

• Deep Intronic Mutation in SERPING1 Caused Hereditary Angioedema Through Pseudoexon Activation

  HUJOVÁ Pavla SOUČEK Přemysl GRODECKÁ Lucie GROMBIŘÍKOVÁ Hana RAVČUKOVÁ Barbora KUKLÍNEK Pavel HAKL Roman LITZMAN Jiří FREIBERGER Tomáš

  Article in Periodical

  Journal of Clinical Immunology, year: 2020, volume: 40, edition: 3, DOI

• Recombinant human C1 esterase inhibitor as short-term prophylaxis in patients with hereditary angioedema

  VALERIEVA Anna STAEVSKA Maria JESENAK Milos HRUBISKOVA Katarina SOBOTKOVA Marta ZACHOVA Radana HAKL Roman ANDREJEVIC Sladjana SUITER Tobias GRIVCHEVA-PANOVSKA Vesna KARADZA-LAPIC Ljerka SOTERES Daniel SHAPIRO Ralph RUMBYRT Jeffrey TACHDJIAN Raffi MEHTA Vinay HSU F. Ida ZANICHELLI Andrea

  Article in Periodical

  JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, year: 2020, volume: 8, edition: 2, DOI