Způsob detekce chromozomální translokace t(11;14)(q13;q32) a oligonukleotidy pro použití při tomto způsobu

Title in English Method of detection of chromosomal translocation t (11; 14) (q13; Q32) and oligonucleotides for use in this way
Authors

TICHÝ Boris ŠUPÍKOVÁ Jana POSPÍŠILOVÁ Šárka MAYER Jiří

Year of publication 2011
Type Patent
MU Faculty or unit

Faculty of Medicine

Publisher Úřad průmyslového vlastnictví
State Czech Republic
Patent's number 302581
Description Method of detection of chromosomal translocation t (11; 14) (q13; Q32) lies in the fact that the DNA obtained from samples of biological material detects the presence of translocation t (11; 14) (q13; Q32) using long-range multiplex PCR (multiplex long -range PCR) using sets of primers covering regions on chromosomes 11 and 14, which usually result in the breakage. The method allows the detection in most samples, in which translocation is present and allows rapid characterization of site-specific design fault detection kits for monitoring minimal residual disease.
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