Nádory plexus choroideus u dětí a adolescentů
| Title in English | Choroid plexus tumors in children and adolescents |
|---|---|
| Authors | |
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Onkologie |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | children; choroid plexus; tumor; chemotherapy; prognosis |
| Description | Tumors of the choroid plexus epithelium were firstly described in 1833. These tumors are rare and represent only 0,5 % of all brain tumors in children and adults. There is some evidence of simian virus 40 participation in their pathogenesis. These tumors can have benign or malignant fenotype, but there are atypical tumors with uncertain biological behaviour. The best treatment remains unknown. Maximal surgical resection is a method of choice and has a prognostic value. The role of an additive treatment is less clear. The first randomized study with the main goal to evaluate the efficacy of adjuvant chemotherapy has been conducted only recently. |