Eotaxin gen -426C-T, -384A-G and 67G-A single-nucleotide polymorphisms and atopic dermatitis in Czech adult AD patients
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Article in Proceedings |
| Conference | 7th Spring Symposium, EADV Cavtat 2010, Chorvatsko, 13.-16.5.2010 - Abstrakta na CD |
| MU Faculty or unit | |
| Citation | |
| Web | http://www.eadvcavtat2010.com |
| Field | Dermatovenerology |
| Keywords | genetic of atopic dermatitis; eotaxin gen |
| Description | Eotaxin may play an important role in atopic dermatitis as a potent immunomodulatory agent. In a pilot study, three single-nucleotide polymorphisms (-426C-T, -384A-G and 67G-A ) of the eotaxin gene were associated with some phenotypes of the AD patients. Detection of this polymorphisms seems to be a promising way for finding of clinically valid gene biomarkers for the disease. |