Activation of adenosine A(3) receptors supports hematopoiesis-stimulating effects of granulocyte colony-stimulating factor in sublethally irradiated mice

Authors

HOFER Michal POSPÍŠIL Milan ŠEVC Luděk DUŠEK Ladislav VACEK Antonín HOLÁ Jiřina HOFEROVÁ Zuzana STREITOVÁ Denisa

Year of publication 2010
Type Article in Periodical
Magazine / Source International Journal of Radiation Biology
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords adenosine; granulocytes; mice
Description The experiments were aimed at testing the ability of N-6-(3-iodobenzyl)adenosine-5'-N-methyluronamide (IB-MECA), an adenosine A(3) receptor agonist, to modulate hematopoiesis in sublethally irradiated mice, when administered alone or in a combination with granulocyte colony-stimulating factor (G-CSF) in a two-day post-irradiation treatment regimen.

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