Diagnostika a výsledky chirurgické léčby infekční endokarditidy
| Title in English | The diagnosis of infective endocarditis and outcomes of its surgical treatment. |
|---|---|
| Authors | |
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | cor et Vasa |
| MU Faculty or unit | |
| Citation | |
| Field | Cardiovascular diseases incl. cardiosurgery |
| Keywords | Infective endocarditis; Diagnosis of infective endocarditis; PCR-based diagnostics |
| Description | Based on investigations of blood culture, culture and PCR-based examination of specimens obtained intraoperatively, the etiologic agent of IE was identified in 98 (83.8%) cases. The sensitivity of detection was highest with PCR-based examination (77.8%) and lowest with culture of intraoperatively recovered specimens (22.2%). Seven patients died within one month, and 16 patients within one year of surgery, resulting in 30-day and one-year mortality rates of 6.2% and 14.2%, respectively. A total of 89 patients were alive after five years resulting in a 78.8% five-year survival rate. Four patients (3.5%) had surgery for relapse of endocarditis. While no significant difference was found in the five-year survival of patients with native-valve versus prosthetic-valve endocarditis, there was a trend toward poorer survival rates in those with the latter condition. |