Dlouhodobé sledování adolescentů po protinádorové léčbě
| Title in English | Long term follow-up in adolescents after antitumour therapy |
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| Authors | |
| Year of publication | 2009 |
| Type | Article in Periodical |
| Magazine / Source | Pediatria |
| MU Faculty or unit | |
| Citation | |
| Field | Paediatry |
| Keywords | Anthracyclines; cardiotoxicity; echocardiohraphz; diastolic function |
| Description | there were evaluated changes of the left ventricle function in 33 asymptomatic patients treated by complex antitumour chemotherapy with anthracyclines for malignancy in childhood (group A) and in 13 patients after finished chemotherapy without antracyclines (group B). The control group (C) included 64 healthy subject. All adolescents were examined using echocardiography. All values were compared between the subgroups. Significant differences in the diastolic left ventricle function were found in patients treated for malignancy in childhood in comparison to healthy population. Significant differences found in the group treated with other drugs (especialy Vinca alcaloids), should be considered for folow-up monitoring. |
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