Expression of COX-2 is associated with accumulation of p53 in pancreatic cancer: analysis of COX-2 and P53 expression inpremalignant and malignant ductal pancreatic lesions
| Authors | |
|---|---|
| Year of publication | 2008 |
| Type | Article in Periodical |
| Magazine / Source | European journal of gastroenterology and hepatology |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | pancreatic cancer |
| Description | These findings confirmed the generally accepted pancreatic cancer progression model, and supported the concept of the interactive role of COX-2 and p53 in pancreatic cancer carcinogenesis, which offers opportunities for targeted therapy and chemoprevention of pancreatic cancer using COX-2 inhibitors. |