Vliv lateralizace fokálních mozkových lézí na stav imunitního systému u pacientů po těžkém poranění mozku
| Title in English | The influence of lateralization of brain lesions on an immune system status in the patients after severe brain injury |
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| Authors | |
| Year of publication | 2006 |
| Type | Article in Proceedings |
| Conference | Kuncův memoriál 2006 |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | severe brain injuries; immune system disorders; lateralization; extracranial inflammatory complications |
| Description | 1, Severe head injuries definitely change cellular as well as humoral part of immune system. Extracranial complications caused by immunity disorders worsen the prognosis. 2, Comparing immune system disorders with various site of brain damage a relevant difference has been disclosed, T– Lymphocytes (CD3+, CD4+) have been lower by the left located damages and their gradual normalization was slower. 3, Various localization of primary as well as secondary brain damage affects immune system in the patients after severe brain injury. The deeper decrease in left located injury group is succeeded by higher occurrence of extra cranial complications and finally it has led to a higher mortality in this group |
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