Regulace aktivity osteoklastů: prostor pro terapii některých onemocnění kostí
| Title in English | Regulation of osteoclast activity: A new approaches in the therapy of bone diseases |
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| Authors | |
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Časopis lékařů českých |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | osteoclasty; diferenciace; osteoporóza; terapie |
| Description | Bone remodeling is process of constant resorption and formation of a bone. Osteoclasts are the cells responsible for bone resorption. Deregulation of osteoclast differentiation, activity or function can result in severe diseases, such as osteoporosis, osteopetrosis or rheumatoid arthritis. Advances in molecular biology of osteoclasts and osteoimmunology open new approaches for specific and efficient therapy. |
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