Příspěvek k problematice diagnostiky tuberkulózy na kosterních pozůstatcích

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Title in English On Diagnosing Tuberculosis from Skeletal Remains
Authors

VARGOVÁ Lenka HORÁČKOVÁ Ladislava

Year of publication 2000
Type Article in Proceedings
Conference Zborník referátov a posterov z antropologických dní s medzinárodnou účasťou 25.-26.10.1999
MU Faculty or unit

Faculty of Medicine

Citation
Field Archaeology, anthropology, ethnology
Keywords tuberculosis; Mycobacterium tuberculosis; DNA; PCR method; bone remains; paleopathology
Description In recent years, five new cases of tuberculosis have been diagnosed from skeletal remains in Moravia. Paleopathological diagnosis was supported by macroscopic, histologic and x-ray examinations.The reliability of these traditional diagnostic procedures was verified by the detection of the Mycobacterium tuberculosis DNA with the aid of the PCR.Macroscopic examination alone was sufficient in the case of the characteristic tuberculous spondylitis from the Krtiny ossarium (13th to 18th c.AD).In the case of coxarthritis from Jihlava (1720s)and of rib periostitis from Hnanice in the Znojmo region (about 4.000 BC),the case of the left tibia from Krtiny (13th to 18thc. AD), in the Olomouc case (12th c. AD), the diagnosis of tuberculosis was reached only with the aid of genetic methods based on the confirmation of the presence of the M. tuberculosis DNA.
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