Fenotypická konverze CYP 2D6 a sexuální dysfunkce
Title in English | Phenotypic conversion of CYP 2D6 and sexual dysfunction |
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Authors | |
Year of publication | 2002 |
Type | Article in Periodical |
Magazine / Source | Klinická farmakologie a farmacie |
MU Faculty or unit | |
Citation | |
Field | Pharmacology and pharmaceutical chemistry |
Keywords | sexual dysfunctions-paroxetine-CYP 2D6-genetic polymorphism |
Description | The paper deals with the incidence of sexual dysfunction within the group of 30 patients on a long-term treatment with paroxetine in coherence with the activity of P 450 CYP 2D6.The stattistic comparison revealed significantly increased occurence of sexual dysfunction in patients with reduced CYP 2D6 metabolic capacity. |
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