Genetic predisposition to metamphetamine dependence - DRD2 and ACE genes

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Authors	ŠERÝ Omar ZNOJIL Vladimír MIKEŠ Vladimír ZVOLSKÝ Petr
Year of publication	2000
Type	Article in Periodical
Magazine / Source	American Journal of Medical Genetics
MU Faculty or unit	Faculty of Science
Citation
Field	Physiology
Keywords	metamphetamine dependence DRD2 I/D ACE polymorphism association
Description	We have investigated the relationship between I/D ACE polymorphism, TaqI A DRD2 polymorphism and metamphetamine dependence. We have found a statistically significant difference (p<0.03) in the I allele frequency between males and females in control group. The results suggest a possibility of the sex effect of the I/D ACE polymorphism to the disposition to the metamphetamine dependence.
Related projects:	Genetic study of alcohol dependence : detection of the association between candidate gene polymorphisms and alcoholism.