Farmakologický profil fosfomycinu

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Title in English Pharmacological profile of fosfomycin
Authors

RYCHLÍČKOVÁ Jitka

Year of publication 2024
Type Article in Periodical
Magazine / Source Klinicka Farmakologie a Farmacie
MU Faculty or unit

Faculty of Medicine

Citation
web https://www.klinickafarmakologie.cz/artkey/far-202404-0002_farmakologicky_profil_fosfomycinu.php
Doi http://dx.doi.org/10.36290/far.2024.022
Keywords fosfomycin; pharmacokinetics; pharmacodynamics; PK/PD characteristics; safety; dosage
Description Fosfomycin, an antibiotic discovered in 1969, is experiencing a renaissance, parti­cularly in the treatment of infections caused by multidrug-resistant Gram-negative pathogens. The combination of its unique mechanism of action, broad spectrum of activity, favourable level of resistance, good tissue penetration and low incidence of adverse events makes it a valuable therapeutic alternative. The aim of this article is to summarize the main pharmacological characteristics of fosfomycin with emphasis on its intravenous form.
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