Thermostable FGF2 Polypeptide, Use Thereof

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Authors	DVOŘÁK Petr KREJČÍ Pavel BÁLEK Lukáš EISELLEOVÁ Lívia KONEČNÁ Žaneta DVOŘÁK Pavel BEDNÁŘ David BREZOVSKÝ Jan ŠEBESTOVÁ Eva CHALOUPKOVÁ Radka ŠTĚPÁNKOVÁ Veronika VAŇÁČEK Pavel PROKOP Zbyněk DAMBORSKÝ Jiří BOSÁKOVÁ Michaela
Year of publication	2023
Type	Patent
MU Faculty or unit	Faculty of Science
Publisher	Intellectual Property India
State	India
Patent's number	IN485239
Web	https://is.muni.cz/publication/2386677/titulni_strana_patentove_listiny.pdf
Attached files	titulni_strana_patentove_listiny.pdf
Description	The present invention relates to engineered Fibroblast Growth Factor 2 (FGF2, bFGF) having improved thermal stability compared to the wild-type and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. The present invention further relates to a culture medium comprising FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells.