Metronomická terapie v léčbě nádorových onemocnění
| Title in English | Metronomic therapy in the treatment of cancer |
|---|---|
| Authors | |
| Year of publication | 2022 |
| Type | Article in Periodical |
| Magazine / Source | Česká a Slovenská Farmacie |
| MU Faculty or unit | |
| Citation | |
| web | Česká a slovenská farmacie |
| Doi | http://dx.doi.org/10.5817/CSF2022-3-91 |
| Keywords | metronomic therapy; antiangiogenic effect; immunomodulatory effect; resistance; toxicity |
| Attached files | |
| Description | Metronomic therapy is a therapeutic method in selected oncological diseases, using long-term administration of low doses of drugs with direct or indirect antitumor effect. In addition, to direct cytotoxic eradication of tumor cells, metronomic therapy can very strongly affect the tumor microenvironment; it also has an immunomodulatory and antiangiogenic effect. Its minimal toxic profile allows for use in patients with severe organ dysfunctions and directly impacts the quality of life and social inclusion of oncological patients. |