Embolizace portální žíly poly(2-hydroxyethylmethakrylátem) před rozsáhlou hepatektomií

Title in English Portal vein embolization prior extended right hepatectomy using poly(2-hydroxyethyl methacrylate)
Authors

PEREGRIN Jan H. KOVÁČ Jozef KAUTZNEROVÁ Dana HONSOVÁ Eva OLIVERIUS Martin KÖCHER Martin ČERNÁ Marie VÁLEK Vlastimil ANDRAŠINA Tomáš PŘÁDNÝ Martin MICHÁLEK Jiří

Year of publication 2014
Type Article in Periodical
Magazine / Source Česká radiologie
MU Faculty or unit

Faculty of Medicine

Citation
Web http://www.cesradiol.cz/dwnld/CesRad_1402_113_119.pdf
Field Other medical specializations
Keywords extended right hepatectomy; portal vein embolization; embolization iduced left liver lobe hypertrophy
Description Aim: Primary aim is to find out if PHEMA (2-hydroxymethacrylate) is suitable for embolization of right liver lobe portal vein in patients indicated for extensive right lobe hepatectomy. Secondary aim is to compare two methods of liver volume estimation: standard liver CT volume calculation and liver volume estimation according to body surface area. Method: Embolization of right liver lobe using PHEMA was performed at three different hospitals in total of 22 patients. Embolization was done from transhepatic approach by retrograde portal vein catheterization. After average 39.7 (10-120) days a hypertrophy of left liver lobe was measured. Left liver lobe posthypertrophic volume was compared to total liver volume calculated by two ways - one from CT volumetry, the other one estimated from body surface area. Results: Technical success was achieved in all procedures; right liver lobe portal vein was occluded in all cases. In 14 patients the volume of left liver lobe increased at least by five percent or more of the total liver volume. We did not experience any complication connected to embolization material property or to the way the embolization was performed. Total liver volumes estimated by two methods differ notably especially in extremely small or big liver. Conclusion: PHEMA proved to be suitable material for portal vein embolization in patients indicated to extended right lobe hepatectomy with predicted too small remnant liver volume postoperatively Both methods recommended for calculation of liver volume could be used, but the results could differ significantly.

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