Závažná reakce typu generalizovaného bulózního fixního lékového exantému po nimesulidu - popis případu
| Title in English | Nimesulid-induced Severe Adverse Reaction of Generalized Bullous Fixed Drug Eruption Type. Case Report |
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| Authors | |
| Year of publication | 2014 |
| Type | Article in Periodical |
| Magazine / Source | Česko-slovenská dermatologie |
| MU Faculty or unit | |
| Citation | |
| Field | Dermatovenerology |
| Keywords | generalized bullous fixed drug eruption; toxic epidermal necrolysis; Stevens-Johnson syndrome; intravenous immunoglobulin; apoptosis; severe adverse drug reactions |
| Description | The authors describe a case of generalized bullous fixed drug eruption after the systemic use of nimesulide successfully treated by an intravenous immunoglobulin. They discuss differential diagnoses particularly Stevens-Johnson syndrome and toxic epidermal necrolysis and provide an overview of current knowledge on the pathogenesis and treatment of this reaction. |