Imunomodulační léčba roztroušené sklerózy mozkomíšní v klinických a zobrazovacích parametrech
Title in English | Clinical and imaging parameters of immunomodulating therapy in multiple sclerosis |
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Authors | |
Year of publication | 2012 |
Type | Article in Periodical |
Magazine / Source | Česká a slovenská neurologie a neurochirurgie |
MU Faculty or unit | |
Citation | |
Field | Neurology, neurosurgery, neurosciences |
Keywords | multiple sclerosis treatment; treatment algorithm; interferon beta; glatiramer acetate; fingolimod; natalizumab; mitoxantrone |
Description | Multiple sclerosis is an inflammatory autoimmune disorder of the central nervous system. Immunomodulating and immunosuppressive drugs have been shown to have partial efficacy but also, sometimes life-threatening, adverse effects. New agents continue to be introduced into the clinical practice and, therefore, treatment algorithm should be regularly updated, to reflect their efficacy, safety profile and evidence-based medicine. |