Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 704
2005
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Cognitive performance in people with Parkinson's disease and mild or moderate depression: effects of dopamine agonists in an add-on to L-dopa therapy.
European Journal of Neurology, year: 2005, volume: 12, edition: 12
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Combined event related fMRI and intracerebral ERP study of an auditory oddball task.
NeuroImage, year: 2005, volume: 26, edition: 1
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Dropped head syndrome in severe intractable epilepsies with mental retardation.
Seizure: European Joural of Epilepsy., year: 2005, volume: 4, edition: 14
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Early sensory ERPs in oddball paradigm (SEEG study)
Book of abstacts, International C.I.A.N.S conference, year: 2005
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Effect of acute and repeated administration of methamphetamine on the activity of CYP2D in isolated perfused rat liver
Acta Veterinaria Brno, year: 2005, volume: 74, edition: 3
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Effect of fluoxetine on methamphetamine biodegradation in methamphetamine dependence
European Neuropsychpharmacology, year: 2005, volume: 2005, edition: 15
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Effect of St John's wort (Hypericum perforatum) on cytochrome P-450 activity in perfused rat liver
Life Sciences, year: 2005, volume: 78, edition: 3
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Electrophysiological response to target and frequent stimuli in a frequency range of 5.5-15 Hz in a visual oddball paradigm
Zborník prác a abstraktov, year: 2005
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Endocrine and immune changes following chronic treatment with tiagabine and amisulpride in the olfactory bulbectomized rat model of depression
European Neuropsychopharmacology, year: 2005, volume: 15, edition: 1
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Endokanabinoidní systém mozku a psychózy
Psychiatrie, year: 2005, volume: 9, edition: 4