prof. MUDr. Michael Doubek, Ph.D.

Head of the research group, Michael Doubek Research Group: Genetic predisposition to hematologic disorders Neuroscience

correspondence Address:
Jihlavská 340/20, 625 00 Brno

phone:	+420 532 23 2144, 3603
e‑mail:

social and academic networks:

Basic information

Supervision

Qualifications

Publications

Type

Total number of publications: 892

2023

FOXO1-RICTOR AXIS induces adaptive increase in AKT activity during BCR inhibitor therapy in CLL: Implications for combination therapy.

ONDRIŠOVÁ Laura ŠEDA Václav CHIODIN Giorgia HLAVÁČ Kryštof KOŠŤÁLOVÁ Lenka FILIP Daniel FARIA ZENI Pedro PANOVSKÁ Anna PLEVOVÁ Karla POSPÍŠILOVÁ Šárka ŠIMKOVIČ Martin VRBACKÝ Filip LYSÁK Daniel FERNANDEZ Stacey M. DAVIDS MS. MAIQUES-DIAZ Alba CHARALAMPOPOULOU Stella MARTIN-SUBERO Jose I. BROWN Jennifer R. DOUBEK Michael FORCONI Francesco MAYER Jiří MRÁZ Marek

Conference abstract

Year: 2023, type: Conference abstract
Foxo1-Rictor axis mediates adaptive increase in Akt activity and cell survival during BCR inhibitor therapy in chronic lymphocytic leukemia.

HLAVÁČ Kryštof ONDRIŠOVÁ Laura ŠEDA Václav HOFERKOVÁ Eva CHIODIN G. KOŠŤÁLOVÁ Lenka MLADONICKÁ PAVLASOVÁ Gabriela FILIP Daniel FARIA ZENI Pedro OPPELT Jan PANOVSKÁ Anna PLEVOVÁ Karla POSPÍŠILOVÁ Šárka ŠIMKOVIČ M. VRBACKÝ F. LYSÁK Daniel FERNANDES SM. DAVIDS MS. MAIQUES-DIAZ A. CHARALAMPOPOULOU S. MARTIN-SUBERO I. BROWN JR. DOUBEK Michael FORCONI Francesco MAYER Jiří MRÁZ Marek

Conference abstract

Year: 2023, type: Conference abstract
Funkční efekt nově identifikované varianty v genu CYCS u rodiny s trombocytopenií typu 4.

ŠTIKA Jiří VRZALOVÁ Zuzana STAŇO KOZUBÍK Kateřina PEŠOVÁ Michaela PALUŠOVÁ Veronika DOSTÁLOVÁ Lenka BLAHÁKOVÁ Ivona RADOVÁ Lenka ŠMÍDA Michal POSPÍŠILOVÁ Šárka DOUBEK Michael

Conference abstract

Year: 2023, type: Conference abstract
Genetická diagnostika familiárních onemocnění krvetvorby.

VRZALOVÁ Zuzana RADOVÁ Lenka STAŇO KOZUBÍK Kateřina ŠTIKA Jiří TRIZULJAK Jakub POSPÍŠILOVÁ Šárka DOUBEK Michael

Conference abstract

Year: 2023, type: Conference abstract
Genetické pozadie progresie Ph-negatívnych myeloproliferácií do sekundárnej akútnej myeloidnej leukémie - kazuistika.

BOHÚNOVÁ Michaela BRYJOVÁ Lenka MAREČKOVÁ Andrea HYNŠT Jakub DOUBEK Michael WEINBERGEROVÁ Barbora POSPÍŠILOVÁ Šárka JAROŠOVÁ Marie KOTAŠKOVÁ Jana

Conference abstract

Year: 2023, type: Conference abstract
Germline variant of CTC1 gene in a patient with pulmonary fibrosis and myelodysplastic syndrome

DOUBKOVÁ Martina VRZALOVÁ Zuzana ŠTEFÁNIKOVÁ Marianna ČERVINEK Libor STAŇO KOZUBÍK Kateřina BLAHÁKOVÁ Ivona POSPÍŠILOVÁ Šárka DOUBEK Michael

Article in Periodical

MULTIDISCIPLINARY RESPIRATORY MEDICINE, year: 2023, volume: 18, edition: June 2023, DOI
Humoral and cellular immune responses to SARS-COV-2 natural infection or vaccination in patients with chronic lymphocytic leukemia (CLL): A study by ERIC, The European research initiative on CLL.

CAMPANELLA A. CHATZIKONSTANTINOU T. DOUBEK Michael KÄTTSTRÖM M. DEMOSTHENOUS Ch. KOTAŠKOVÁ Jana ZALESKA J. GHIA P.

Conference abstract

Year: 2023, type: Conference abstract
Charakteristika a výsledky léčby Ropegenterferonem ALFA2B u pacientů s Ph negativními myeloproliferacemi.

PODSTAVKOVÁ N. WEINBERGEROVÁ Barbora KVETKOVÁ Anežka BOHÚNOVÁ Michaela MAREČKOVÁ A. KOTAŠKOVÁ Jana JEŽÍŠKOVÁ Ivana DOUBEK Michael MAYER Jiří

Conference abstract

Year: 2023, type: Conference abstract
Chronická lymfocytární leukemie

PANOVSKÁ Anna BRYCHTOVÁ Yvona DOUBEK Michael

Chapter of a book

Klinická onkologie, edition: Vyd. 1, year: 2023, number of pages: 3 s.
IKZF1 alterations have a negative impact on early molecular response and survival of adult patients with B-cell precursor acute lymphoblastic leukemia treated treated with GMALL 07/2003 protocol in Czechia.

POLÍVKOVÁ V. HRABOVSKÝ Štěpán VRZALOVÁ Zuzana ŠTIKA Jiří HORÁČEK Jan PECHERKOVÁ Pavla HALÁMOVÁ Hana ZUNA Jan TRKA Jan FROŇKOVÁ Eva ZALIOVÁ Markéta DOUBEK Michael MACHOVÁ POLÁKOVÁ Kateřina ŠÁLEK C

Conference abstract

Year: 2023, type: Conference abstract

Projects

Teaching