Manlio Vinciguerra, PhD.

2024

• Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant

  FRÖHLICH Jan LIORNI Niccolo MANGONI Manuel LOCHMANOVÁ Gabriela PÍREK Pavlína KAŠTÁNKOVÁ Nikola PATA Pille KUČERA Jan CHALDAKOV George N TONCHEV Anton B PATA Illar GORBUNOVA Vera LEIRE Eric ZDRÁHAL Zbyněk MAZZA Tommaso VINCIGUERRA Manlio

  Article in Periodical

  CLINICAL EPIGENETICS, year: 2024, volume: 16, edition: 1, DOI

2023

• Detection of cell-free histones in the cerebrospinal fluid of pediatric central nervous system malignancies by imaging flow cytometry

  BUZOVA Diana FROHLICH Jan ZAPLETALOVÁ Danica RAFFAELE Marco LO RE Oriana TSONEVA Desislava K ŠTĚRBA Jaroslav CERVENY Jan VINCIGUERRA Manlio

  Article in Periodical

  Frontiers in Molecular Biosciences, year: 2023, volume: 10, edition: November 2023, DOI

2022

• GDF11 inhibits adipogenesis and improves mature adipocytes metabolic function via WNT/beta-catenin and ALK5/SMAD2/3 pathways

  FROHLICH Jan KOVACOVICOVA Kristina RAFFAELE Marco VIRGLOVA Tereza CIZKOVA Eliska KUČERA Jan DOBROVOLNÁ Julie WABITSCH Martin PEYROU Marion BONOMINI Francesca REZZANI Rita CHALDAKOV George N. TONCHEV Anton B. DI ROSA Michelino BLAVET Nicolas HEJRET Václav VINCIGUERRA Manlio

  Article in Periodical

  Cell Proliferation, year: 2022, volume: 55, edition: 10, DOI

• Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs

  GIALLONGO Sebastiano REHAKOVA Daniela BIAGINI Tommaso LO RE Oriana RAINA Priyanka LOCHMANOVÁ Gabriela ZDRÁHAL Zbyněk RESNICK Igor PATA Pille PATA Illar MISTRIK Martin DE MAGALHAES Joao Pedro MAZZA Tommaso KOUTNÁ Irena VINCIGUERRA Manlio

  Article in Periodical

  Stem Cells, year: 2022, volume: 40, edition: 1, DOI

2021

• Redox and Epigenetics in Human Pluripotent Stem Cells Differentiation

  GIALLONGO Sebastiano ŘEHÁKOVÁ Daniela RAFFAELE Marco LO RE Oriana KOUTNÁ Irena VINCIGUERRA Manlio

  Article in Periodical

  ANTIOXIDANTS & REDOX SIGNALING, year: 2021, volume: 34, edition: 4, DOI

2020

• A Lipidomic Signature Complements Stemness Features Acquisition in Liver Cancer Cells

  SERNA I. M. R. ROMITO I. MAUGERI A. LO RE Oriana GIALLONGO Sebastiano MAZZOCCOLI G. OBEN J. A. LI VOLTI G. MAZZA T. ALISI A. VINCIGUERRA Manlio

  Article in Periodical

  International Journal of Molecular Sciences, year: 2020, volume: 21, edition: 22, DOI

• Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4(+)CD25(+)FoxP3(+) regulatory T cells activation

  LO RE Oriana MAZZA Tommaso GIALLONGO Sebastiano SANNA Paola RAPPA Francesca LUONG Tu Vinh Luong VOLTI Giovanni DVOŘÁKOVÁ Adéla ROSKAMS Tania VAN HAELE Matthias TSOCHATZIS Emmanuel VINCIGUERRA Manlio

  Article in Periodical

  THERANOSTICS, year: 2020, volume: 10, edition: 2, DOI

• Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells

  GIALLONGO Sebastiano DI ROSA M. CALTABIANO R. LONGHITANO L. REIBALDI M. DISTEFANO A. LO RE Oriana AMORINI A. M. PUZZO L. SALVATORELLI L. PALMUCCI S. TIBULLO D. RUSSO A. LONGO A. LAZZARINO G. LI VOLTI G. VINCIGUERRA Manlio

  Article in Periodical

  AGING-US, year: 2020, volume: 12, edition: 10, DOI

• Senescence-like phenotype in post-mitotic cells of mice entering middle age

  RAFFAELE Marco KOVAČOVICOVÁ Kristína BONOMINI Francesca REZZANI Rita FROHLICH Jan VINCIGUERRA Manlio

  Article in Periodical

  AGING-US, year: 2020, volume: 12, edition: 14, DOI

2019

• Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome

  BERESHCHENKO Oxana LO RE Oriana NIKULENKOV Fedor FLAMINI Sara KOTAŠKOVÁ Jana MAZZA Tommaso LE PANNERER Marguerite-Mari BUSCHBECK Marcus GIALLONGO Cesarina PALUMBO Giuseppe LI VOLTI Giovanni PAZIENZA Valerio ČERVINEK Libor RICCARDI Carlo KREJČÍ Lumír POSPÍŠILOVÁ Šárka STEWART A. Francis VINCIGUERRA Manlio

  Article in Periodical

  CLINICAL EPIGENETICS, year: 2019, volume: 11, edition: 1, DOI