doc. RNDr. Alena Hyršlová Vaculová, Ph.D.

2024

• Inhibition of Chk1 stimulates cytotoxic action of platinum-based drugs and TRAIL combination in human prostate cancer cells

  KRKOŠKA Martin PARUCH Kamil ŠOŠOLÍKOVÁ Tereza VÁZQUEZ-GÓMEZ Gerardo HERŮDKOVÁ Jarmila NOVOTNÝ Jan OVESNÁ Petra SOVA Petr HYRŠLOVÁ VACULOVÁ Alena

  Article in Periodical

  Biological Chemistry, year: 2024, volume: 405, edition: 6, DOI

2022

• Role of miR-653 and miR-29c in downregulation of CYP1A2 expression in hepatocellular carcinoma

  KRKOŠKA Martin NEKVINDOVA Jana NEVĚDĚLOVÁ Kateřina ZUBANOVA Veronika RADOVÁ Lenka VONDRACEK Jan HERUDKOVA Jarmila SLABÝ Ondřej KISS Igor BOHOVICOVÁ Lucia FABIAN Pavel TYLICHOVA Zuzana KALA Zdeněk KYSELA Petr OSTŘÍŽKOVÁ Lenka PALICKA Vladimir HYRŠLOVÁ VACULOVÁ Alena

  Article in Periodical

  Pharmacological Reports, year: 2022, volume: 74, edition: 1, DOI

2021

• CHK1 INHIBITOR SCH900776 ENHANCES ANTICANCER ACTION OF CISPLATIN AND TRAIL VIA STIMULATION OF BAK-DEPENDENT MITOCHONDRIAL PATHWAY

  KRKOŠKA Martin PARUCH Kamil HYRŠLOVÁ VACULOVÁ Alena HERŮDKOVÁ Jarmila

  Conference abstract

  Year: 2021, type: Conference abstract

2018

• INHIBITION OF P300/CBP REDUCES CYP1A1 INDUCTION IN CANCER CELL MODELS DERIVED FROM THE LIVER OR COLON EPITHELIUM

  KRKOŠKA Martin SVOBODOVÁ Jana ZAPLETAL Ondřej KARASOVÁ Martina HYRŠLOVÁ VACULOVÁ Alena VONDRÁČEK Jan

  Conference abstract

  Year: 2018, type: Conference abstract

2017

• Dietary fatty acids specifically modulate phospholipid patternin colon cells with distinct differentiation capacities

  HOFMANOVÁ Jiřina SLAVÍK Josef OVESNÁ Petra TYLICHOVÁ Zuzana VONDRÁČEK Jan STRAKOVÁ Nicol HYRŠLOVÁ VACULOVÁ Alena CIGANEK Miroslav KOZUBÍK Alois KNOPFOVÁ Lucia ŠMARDA Jan MACHALA Miroslav

  Article in Periodical

  European Journal of Nutrition, year: 2017, volume: 56, edition: 4, DOI

• Chk1 Inhibitor SCH900776 Effectively Potentiates the Cytotoxic Effects of Platinum-Based Chemotherapeutic Drugs in Human Colon Cancer Cells

  HERŮDKOVÁ Jarmila PARUCH Kamil KHIRSARIYA PrashantKumar SOUČEK Karel KRKOŠKA Martin VONDÁLOVÁ BLANÁŘOVÁ Olga SOVA Petr KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Article in Periodical

  Neoplasia, year: 2017, volume: 19, edition: 10, DOI

• INHIBITION OF CHK1 STIMULATES THE COOPERATIVE CYTOTOXIC ACTION OF PLATINUM-BASED DRUGS AND TRAIL IN HUMAN PROSTATE CANCER CELLS

  KRKOŠKA Martin HERŮDKOVÁ Jarmila BLANÁŘOVÁ O Vondálová PARUCH Kamil SOVA P HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2017, type: Conference abstract

• PLATINUM-BASED DRUG-MEDIATED INCREASE OF TRAIL-INDUCED PROSTATE CANCER CELL APOPTOSIS DEPENDS ON MITOCHONDRIA BUT NOT CASPASE-10

  VONDÁLOVÁ BLANÁŘOVÁ Olga ŠAFAŘÍKOVÁ Barbora HERŮDKOVÁ Jarmila KRKOŠKA Martin ANDĚRA Ladislav SOVA P HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2017, type: Conference abstract

• The role of Chk1 in regulation of apoptosis induced by platinum-based drugs in human prostate cancer cells

  KRKOŠKA Martin HERŮDKOVÁ Jarmila BLANÁŘOVÁ Olga Vondálová PARUCH Kamil SOVA Petr HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2017, type: Conference abstract

2016

• Cisplatin or LA-12-mediated stimulation of TRAIL-induced apoptosis in human prostate cancer cells involves Bax/Bak-dependent mitochondria activation

  VONDÁLOVÁ BLANÁŘOVÁ Olga HERŮDKOVÁ Jarmila ŠAFAŘÍKOVÁ Barbora KRKOŠKA Martin TOMÁNKOVÁ Silvie PERNICOVÁ Zuzana SOUČEK Karel BOUCHAL Jan KHARAISHVILI G KRÁL M SOVA P HOFMANOVÁ Jiřina KOZUBÍK Alois HYRŠLOVÁ VACULOVÁ Alena

  Conference abstract

  Year: 2016, type: Conference abstract