Determination of Biologically Active Compounds in Medicinal Plants by Capillary Electrochromatography

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Authors

KVASNIČKOVÁ Leona ŠTĚRBOVÁ Hana GLATZ Zdeněk KAHLE Vladislav SLANINA Jiří

Year of publication 2001
Type Article in Proceedings
Conference Book of abstract 2nd International symposium "Separations in BioSciences SBS 2001"
MU Faculty or unit

Faculty of Science

Citation
Field Biochemistry
Keywords CEC; Schizandra
Description Schizandra chinensis is native in East Asia, but several attempts to cultivate this plant under European climatic conditions have been made. The biologically active compounds are the lignans with an uncommon structure derived from dibenzo[a,c]cyclooctadiene. The lignans prevent liver injuries induced by some hepatotoxic chemicals, stimulate liver regeneration after partial hepatoctonomy and also inhibit hepatocarcinogenesis and lipid peroxidation in rats. CEC in macroporous polyacrylamide columns were successfully used to analyse and quantify lignans in extract of the seeds of S. chinensis. Good separations were achieved in less than 35 min.
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