TGF-beta1 gene polymorphisms
| Autoři | |
|---|---|
| Rok publikování | 2001 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Allergy |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Genetika a molekulární biologie |
| Klíčová slova | gene; polymorphism; allergy; TGF; asthma |
| Popis | Transforming growth factor beta (TGF-beta) is a pleiotropic cytokine with significant anti-inflammatory and immunosuppressive properties. The single base pair polymorphism located at -509 (C/T) in the promoter region of the TGF-beta1 gene was previously shown to be associated with elevated total serum IgE levels. We tested the hypothesis that polymorphic alleles of the TGF-beta1 gene are associated with allergies and asthma. |
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