Structure of Chelerythrine Base
| Autoři | |
|---|---|
| Rok publikování | 1995 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Journal of Natural Products |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Organická chemie |
| Klíčová slova | Chelerythrine Base; alkaloids |
| Popis | The structure of chelerythrine free base was examined. When chelerythrine chloride [1b] was treated with aqueous K2CO3 solution, bis[6-(5,6-dihydrochelerythrinyl)] ether [3] was obtained. An excess of aqueous ammonia under the same conditions yielded bis[6-(5,6-dihydrochelerythrinyl)] amine [4]. The structures of both derivatives were determined by elemental analysis, ir, 1D and 2D nmr, eims, and cims. The formation of an unstable hydroxy adduce 2a (pseudobase) was observed in H-1-nmr experiments only. |