A systematic review on correlation between biochemical and mechanical processes of lubricant film formation in joint replacement of the last 10 years

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Publikace nespadá pod Lékařskou fakultu, ale pod Přírodovědeckou fakultu. Oficiální stránka publikace je na webu muni.cz.
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RUFAQUA Risha VRBKA Martin CHOUDHURY Dipankar HEMZAL Dušan KŘUPKA Ivan HARTL Martin

Rok publikování 2019
Druh Článek v odborném periodiku
Časopis / Zdroj Lubrication Science
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
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Doi http://dx.doi.org/10.1002/ls.1452
Klíčová slova bio-tribology; film formation; Raman spectroscopy; synovial fluid; tribo-chemistry
Popis This study provides a systematic review of the synovial and simulated body fluid research for the last 10years (2006 to 2016). In particular, biochemical and mechanical properties of synovial fluid after joint replacement are focused, namely, the chemical composition of the formed lubricating film and structural changes of the associated proteins under mechanical loading. In summary, the formation of the film depends on pH, viscosity, and concentration of the solution, static, sliding, and rolling conditions and other factors related to the joint replacement. However, chemical changes of the synovial fluid proteins after the joint replacement are rarely addressed and require further attention. To this end, we provide a preliminary study of selected proteins within the synovial fluid using Raman spectroscopy. We conclude that chemical analysis together with the analysis of mechanical and biological properties of the synovial fluid after total joint replacement will help in comprehension of the process.
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