AHEAD score - Long-term risk classification in acute heart failure
| Autoři | |
|---|---|
| Rok publikování | 2016 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | International Journal of Cardiology |
| Fakulta / Pracoviště MU | |
| Citace | |
| Doi | http://dx.doi.org/10.1016/j.ijcard.2015.08.187 |
| Obor | Kardiovaskulární nemoci včetně kardiochirurgie |
| Klíčová slova | Acute heart failure; Prognosis; Model; Mortality |
| Popis | Background: The role of co-morbidities in the prognosis of patients hospitalized for AHFwas examined using the AHEAD (A — atrial fibrillation, H — haemoglobin b 130 g/l for men and 120 g/l for women (anaemia), E — elderly (age N 70 years), A — abnormal renal parameters (creatinine N 130 micromol/l), D — diabetes mellitus) scoring system. Methods: AHEAD — multicentre prospective Czech registry of AHF patients; GREAT registry — international cohort of AHF patients. Data from 5846 consecutive patients hospitalized for AHF (AHEAD registry; derivation cohort) were analysed to build the AHEAD score. Each risk factor of the AHEAD score was counted as 1 point. The model was validated externally using an international cohort of similar patients in the GREAT registry (6315). Results:Main outcome was one year all-cause mortality. The mean age of patientswas 72±12 years,with 61.6% of patients aged N70 years; 43.4% were women. Atrial fibrillation was present in 30.7%, anaemia in 38.2%, creatinine N130mmol/l (abnormal renal parameters) in 30.1%, and diabetes mellitus in 44.0%. The mean AHEAD score was 2.1. In patients with AHEAD scores of 0–5, the one-year mortality rates were 13.6%, 23.4%, 32.0%, 41.1%, 47.7%, and 58.2%, respectively (p b 0.001), and the 90 month mortality rates were 35.1%, 57.3%, 73.5%, 84.8%, 88.0%, and 91.7%, respectively (p b 0.001). Conclusion: The AHEAD is a simple scoring system based on the analysis of co-morbidities for the estimation of the short and long term prognosis of patients hospitalized for AHF. |
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