Sperm meiotic segregation, aneuploidy and high risk of delivering an affected offspring in carriers of non-Robertsonian translocation t(13;15)

Autoři	KAŠÍKOVÁ Kateřina VOZDOVÁ Miluše PETRA Přinosilová GAILLYOVÁ Renata HANÁKOVÁ Marta RUBEŠ Jiří
Rok publikování	2012
Druh	Článek v odborném periodiku
Časopis / Zdroj	Journal of Assisted Reproduction and Genetics
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
Doi	http://dx.doi.org/10.1007/s10815-012-9767-1
Obor	Genetika a molekulární biologie
Klíčová slova	Chromosomal translocation; Sperm FISH; Meiotic segregation; Interchromosomal effect; Aneuploidy
Popis	Since the proportions of unbalanced spermatozoa and the risk of delivering an affected offspring are high, prenatal or preimplantation genetic diagnosis is recommended for such patients.