Informace o projektu
Molecular organization of the zygotic spindle apparatus in non-rodent embryos
- Kód projektu
- MUNI/IGA/1127/2021
- Období řešení
- 1/2022 - 12/2022
- Investor / Programový rámec / typ projektu
-
Masarykova univerzita
- Interní grantová agentura MU
- Fakulta / Pracoviště MU
- Lékařská fakulta
Despite scientific advances in reproductive medicine, embryo development still holds a myriad of secrets. The reset of the cell cycle machinery driving the unification and segregation of two parental genomes in the fertilized egg is fundamental to all mammals. The proposed work will shed new light on basic cell cycle mechanisms underlying the transition from acentrosomal female meiosis to the first mitotic division in which sperm centrioles assume control of microtubule organization.
Publikace
Počet publikací: 3
2024
-
Zygotic spindle orientation defines cleavage pattern and nuclear status of human embryos
Nature Communications, rok: 2024, ročník: 15, vydání: 1, DOI
2022
-
ONE STEP CHEMICAL DERIVATIZATION OF SECRETED CELL METABOLITES FOR SENSITIVE MASS SPECTROMETRY DETECTION
Rok: 2022, druh: Konferenční abstrakty
-
The first cleavage plane in human embryos is dictated by the topology of pronuclei, not by the polar body position
Rok: 2022, druh: Konferenční abstrakty