Informace o projektu
Plazmové polymery připravené na nanovlákenných membránách pro inženýrství cévní tkáně
- Kód projektu
- GA18-12774S
- Období řešení
- 1/2018 - 12/2020
- Investor / Programový rámec / typ projektu
-
Grantová agentura ČR
- Standardní projekty
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
- Spolupracující organizace
-
Fyziologický ústav AV ČR, v. v. i.
- Odpovědná osoba Mgr. Martin Pařízek, Ph.D.
Project will provide insight into the deposition of plasma polymers with varied nitrogen and oxygen content that are promising for bioapplications including tissue engineering. Understanding the film structure influenced by the power invested into the plasma and leading to the gas-phase dissociation and chemical reactions together with the effect of ions delivering energy towards the growing film is a necessary step for tuning the deposition towards the specific and demanding requirements. The investigation of factors influencing the adhesion and proliferation of endothelial and vascular smooth muscle cells in cultures on plasma polymers with varied chemical composition, cross-linking, stability and reactivity towards ECM proteins will unravel the complex and up-to-now unclear relationships. Their deeper understanding will help
to make advances in engineering of materials for vascular tissues, especial because we will combine plasma polymers with electrospun polymer nanofibers into one unique material with tunable microstructure, surface chemistry and biodegradability.
Publikace
Počet publikací: 11
2023
-
Molecular dynamics simulation of amine formation in plasma-enhanced chemical vapor deposition with hydrocarbon and amino radicals
Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films, rok: 2023, ročník: 41, vydání: 6, DOI
2021
-
Amine modification of calcium phosphate by low-pressure plasma for bone regeneration
Scientific Reports, rok: 2021, ročník: 11, vydání: 1, DOI
-
Deposition Penetration Depth and Sticking Probability in Plasma Polymerization of Cyclopropylamine
Applied Surface Science, rok: 2021, ročník: 540, vydání: February 2021, DOI
-
Exploring the Emission Pathways in Nitrogen-Doped Graphene Quantum Dots for Bioimaging
Journal of Physical Chemistry C, rok: 2021, ročník: 125, vydání: 38, DOI
2020
-
Behaviour of Vascular Smooth Muscle Cells on Amine Plasma-Coated Materials with Various Chemical Structures and Morphologies
International Journal of Molecular Sciences, rok: 2020, ročník: 21, vydání: 24, DOI
-
Cell type specific adhesion to surfaces functionalised by amine plasma polymer
Scientific Reports, rok: 2020, ročník: 10, vydání: 1, DOI
-
Modeling characterisation of a bipolar pulsed discharge
Plasma Sources Science and Technology, rok: 2020, ročník: 29, vydání: 10, DOI
-
Molecular dynamics simulation of amine groups formation during plasma processing of polystyrene surfaces
Plasma Sources Science and Technology, rok: 2020, ročník: 29, vydání: 10, DOI
-
Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing
Polymers, rok: 2020, ročník: 12, vydání: 6, DOI
2019
-
Homogeneity and Penetration Depth of Atmospheric Pressure Plasma Polymerization onto Electrospun Nanofibrous Mats
Applied Surface Science, rok: 2019, ročník: 471, vydání: March, DOI