Effect of shift-work on the circadian rhythm of blood pressure

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CORNELISSEN G. HAVELKOVÁ Alena GIERKE C. L. LUNDEEN L. S. SIEGELOVÁ Jarmila

Rok publikování 2019
Druh Článek ve sborníku
Konference Noninvasive methods in cardiology 2019
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://is.muni.cz/do/med/noninvasive_methods_in_cardiology/noninvasive_methods_in_cardiology_2019.pdf
Popis Shift work and the circadian disruption it creates have been implicated in the increased risk of a number of disease conditions, cardiovascular disease in particular. Ambulatory blood pressure monitoring is well suited to assess deviations from norms indicative of a heightened cardiovascular risk. Herein, we report on a case-control study comparing circadian rhythm characteristics of 10 clinically healthy nurses working shifts with those of 10 clinically non-shifting healthy peers selected from the same Brno 7-day/24-hour ABPM database to match shift workers by sex, age, and body mass index. On average, shift-workers were found to have a higher blood pressure MESOR than their non-shifting counterparts. Analysis of separate 24-hour spans of records from the shift-workers corresponding to different shift schedules (daytime, nighttime, or free day) also indicates that night shift is associated with a weaker circadian variation in blood pressure. These results confirm those of previous studies. Their implication of a weakened circadian rhythm on night shifts may underlie the increased cardiovascular disease risk observed in relation to shift work.

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