snímek PPT
Plasma concentration of solutes (PX) is disturbed by extrarenal load. On the other hand, it itself interferes with individual components of EL (with production, supply, metabolism, and storage of a substance).
PX is corrected by renal excretion. However, it must have a possibility to modify the excretion in a feebdback manner; this is realized by a direct, trivial manner during filtration, or indirectly by neural and hormonal feedbacks (Fig. 2)