snímek PPT
- Lymphokines: Proteins secreted by some helper T cells after they are primed by contact with an antigen. Are not antibodies but are mediators of cellular immunity. They activate various white blood cells, incl. other lymphocytes. Examples: interleukin 2, some interferons, migration inhibition factor (MIF)
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- Tumor necrosis factors: have cytotoxic effects on tumor cells but not on normal cells. TNF? is secreted by macrophages in response to bacterial infection and other challenges, TNF? by helper T lymphocytes and cytotoxic lymphocytes. Synergistic with interferons