snímek PPT
Mother 0 has antibodies against A and B already spontaneously (in contradisticition to Rh- mothers, in whom the antibodies not are formed before the first parturition), and these reach the foetus via placenta. Not easily, however – they are IgM, therefore large molecules, so the symptoms are mild
Antigen-antibody complexes ? complement
activation ? premature lysis of RBC
Rh incompatibility – (Fig. 29)