snímek PPT
Fe storage normal or ?
Besides
- ? EPO production or its binding to the stem
cells (loss of EPO receptors, disturbed
coupling)
Etiopathogenesis: foreign antigenes pertaining to
the inflammatory process ? activation of
macrophages ?
Il-1 and TNF production: ? Fe metabolism in
MF disturbed; direct inhibition of EPO
production
Conditions: chronic inflammations (e.g. hepatitis),
some malignancies, collagen-vascular diseases