snímek PPT
Other microcytic-hypochromic anemias
Abnormalities of the heme or globin synthesis ?
?Hb production ? more than 4 divisions ?
microcytosis and hypochromia
Unavailability of iron to blast cells - Anemia of
chronic disease (ACD)
Block of Fe metabolism: macrophages
degrading Hb of the decayed RBC are activated,
proliferate and retain Fe for themselves
? hepatic syntheses ? ?transferrin together with
plasma Fe
(Fig. 23)