Unraveling the Impact of High Glucose on the Retina: Insights from Human Retinal Organoids
Diabetic retinopathy (DR) remains a leading cause of vision loss worldwide, yet despite significant advancements in ophthalmology and diabetes research, there is still much to uncover about its early onset and progression. Traditionally viewed as a vascular disease, recent studies—including ours—suggest that neurodegeneration may occur even before vascular damage. But what exactly happens at a cellular and molecular level when the retina is exposed to high glucose?